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In context

Nonapeptide-1 has been investigated as an ingredient in a proprietary topical combination for melasma maintenance. [1]

Editorial basisLinked primary sources
Source checked2026-11-07
Clinical reviewNo named medical review

At a glance

Type
Topical cosmetic ingredient
Regulatory context
The cited source describes research, not a determination of present marketing authorisation. Country, formulation and indication must be checked separately.
Evidence
A combination-product trial cannot isolate one ingredient's contribution. Findings for a topical formula do not establish injected use or a general skin-lightening indication.

How to interpret this evidence

A combination-product trial cannot isolate one ingredient's contribution. Findings for a topical formula do not establish injected use or a general skin-lightening indication. [1]

Safety and clinical context

Topical cosmetic research does not support injection or other systemic use. Safety and tolerability depend on the complete formulation and the person using it.

Evidence and authorisation depend on the product, formulation, indication and country. US labelling does not establish Thai authorisation. This guide is educational and is not a dosing or self-treatment protocol.

Primary sources

Read the underlying source and its limitations. A study citation does not by itself establish efficacy or approval.

  1. A randomized controlled pilot study of a proprietary combination versus sunscreen in melasma maintenance. pubmed.ncbi.nlm.nih.gov

How we use evidence and describe review

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